Father cutting baby's cord Newborn baby with cord still attached Cord with placenta attached
  1. Benefits Of Cord Blood

    There seems to be a raging debate going on right now over cord blood. Not whether or not cord blood can benefit people because most medical professionals agree that the stem cells found in cord blood can be of great benefit for a host of illnesses from sickle cell anemia to leukemia. In fact, recent research suggests that stem cells may be able to successfully treat over 70 diseases. The debate seems to be who the cord blood can benefit.

    In order to clearly understand the debate, it helps to know exactly what cord blood is and why it is considered so special. Cord blood is blood that is taken from the umbilical cord of newborn babies immediately after birth. Since the baby is all ready born and no longer needs the cord for nutrients, taking this blood does not hurt either the mother or the child and in fact, if the cord blood is not taken it simply remains in the cord and is disposed of.

    Cord blood is considered important because it contains stem cells which are building block of the entire immune system. When people suffer from diseases of the immune system using cord blood could help build up the immune system to help fight the disease.

    The Push For Cord Blood Storage

    In recent years there pregnant women have been inundated through pamphlets, magazines articles, and other types of media claiming that saving their babies cord blood could save their child or a family member at some future date.

    These articles and stories play heavily on a mother’s desire to protect her child and the rest of the family and uses heavy handed tactics to make them feel guilty and less of parent if they don’t pay the $1000 or more initial fee to have this blood taken and stored and then continue to pay $100.00 a year to keep it stored for the future.

    What these articles and such produced by private blood banks don’t tell these women is that there is little chance that their family will ever use this cord blood. This is where the heated debate comes in. Doctors across the country compare these private blood banks to snake oil salesmen claiming they pray on pregnant women and couples to turn a profit for something that will never be used.

     How Cord Blood Really Benefits People

    The true benefits of cord blood is not in storing it in a private blood bank where you may spend 20 years paying fees for something that will not ever be used, but, in a public bank where this blood may be used by those who desperately need it, when they need it. Many doctors point out that donated cord blood to public blood banks won’t cost the parents a penny.

    Because cord blood does not have to be a perfect match to the recipients blood, it is easier for people needing the stem cells to find a match and since these stem cells come from infants whose immune system is not developed at the time, there is less likelihood of the this blood battling against the recipients old blood and causing complications from rejections.

    However, due to the lack of cord blood donations in public blood banks, people still remain on waiting lists while cord blood that may match a needy patient sits unused in private blood banks.

    To make matters worse, since cord blood collection is still somewhat new, not every hospital is qualified to collect this blood. It is estimated that somewhere between 75 and 90% of parents cannot donate their babies cord blood simply because of where they live.

    As more and more conditions are helped by the stem cells in cord blood, and as the demand increases this will change but, change as always is slow. However, the real benefits of cord blood will never truly be realized until there is enough cord blood available for all those who need it.

    Private blood banks

    In the meantime, private blood banks will continue to frighten expectant parents and collect their fat fees while people who may have benefited from that privately stored cord blood continue to wait and hope for matching cord blood to become available that will benefit them.

    While some minute portion of these families may eventually use this privately stored cord blood for the majority of these families they will be out thousands of dollars, and in the end, the cord blood will be of no benefit to anyone.

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  2. Stem Cell Research For Spinal Cord Injuries

    Stem cell research for spinal cord injuries covers wide territory. Some researchers focus their attention on using the stem cell research for spinal cords to create new myelin sheath cells and others simply want to improve the quality of the patients life regardless of the process. While most of the studies such as these are on lab rats, rather than human patients, a study using autologous stem bone marrow derived stem cells on human victims of spinal cord injury showed an improvement in the quality of life of the victims.   

    Reeve-Irvine Research Center

    In Irvine, California at the Reeve-Irvine Research Center, University of California, Hans Keirstead and a group of colleagues used rats to study the effects of human embryonic stem cell treatment to restore motor skills they lost when they suffered acute damage to the spinal cord tissue. Their focus was on the restoration of the myelin sheath.

    They myelin sheath is insulation tissue for neurons and mandatory for the conduction of electrical messages through the nervous system. If you look at the nerves as being similar to an extension cord and the spinal cord as the one that plugs directly into the outlet, when spinal cord injury occurs, it’s similar to slicing away some of the outside insulation on an electrical cord. The electricity never reaches the fixture that needs it for energy. In the case of the spinal column and myelin, the message from the brain to the extremities is lost at the site of the missing myelin.

    Working from that information, the team at UC Irvine concluded that if you focused on repairing the sheath, you would restore lost neurological function. Earlier studies by the group showed the body’s own immune stem attacked the myelin and destroyed it after injury to the spinal cord. Initial studies showed that if they used antibodies suppressing that response, the myelin could regenerate and therefore restore the lost functions.

    The team at UCI then used a method to encourage the stem cells to develop into oigodendrocyte cells, which are the building blocks necessary for the formation of myelin. In rats given the treatment with stem cells for spinal cord injury, within 7 days after injury, the cells did for the myelin tissue and wrap around the area of damage. After just two months, these injured rats walked. Their counterparts that received no treatment did not.

    The scientists wondered whether this treatment could help previously injured victims. They injected the cells into a group of rats 10 months after injury. While the early-stage cells formed mature oligodendrocyte cells in both groups and traveled to the spinal cord, they could not grow because scar tissue filled the neuron cells and inhibited the myelin growth.

    Karolinska Institutet

    Karolinska Institutet, Stockholm Sweden, had similar results. However, they found that there were some problems with the use of stem cells for spinal cord injury. While it restored function, it also increased pain sensitivity in the rats. In order to avoid this, the scientists used a special gene in the stem cells, neurogenin-2 when they developed them in the culture. The hypothesis on the increased pain was that some of the cells developed in to a type of glial cell called astrocytes. These cells tend to cause pain axons to grow in the spinal cord with the secretion of substances that stimulate the development of neuronal cells.

    The group also noted that the increased number of oligondendrocyte cells produced by the neurogenin-2 stem carrying stem cells, corresponded to a higher amount of myelin-coated nerves, white material, in the area of the damage.

    The team at Karolinska Institutet used fMRI, functional Magnetic Resonance Imaging, to demonstrate the restoration of the sensory function. This technique, use at the institute’s experimental MRI location has an advantage. If experiments start on humans, the fMRI is one method of comparing results in the human studies.  

    Krembil Neuroscience Center

    The work at the Krembil Neuroscience Center in Toronto Western Research Institute and the University of Toronto also noted that there was a window critical to the effectiveness of stem cell transplants. They added a combination of immune suppressing drugs and growth factors into the therapy and transplanted stem cells from the brains of adult rats into the crushed spines of injured rats. Over a third of the cells traveled to the area of injury and created tissues like those destroyed at the area, including myelin. As with the California study, the Toronto study showed that the process worked best soon after the injury and failed to work if done too late in the healing process.

    Another study called “Activated Spinal Cord Ependymal Stem Cells Rescue Neurological Function” published by Moreno-Manzano, V., Rodríguez-Jiménez, F. J., García-Roselló, M., Laínez, S., Erceg, S., Calvo, M. T., Ronaghi, M., Lloret, M., Planells-Cases, R., Sánchez-Puelles, J. M. and Stojkovic, M. in 2009, shows the stem cells in the spinal cord lining called ependymal stem cells, reverses paralysis that often occurs with spinal cord injury. These cells are multiples higher in those with a spinal cord injury than with healthy subjects.

    Once the transplant subject formed a lesion, the use of stem cells was more effective at creating the types of cells necessary for the repair of the area. While the study was an animal study, the information gleaned can help scientist understand the working mechanisms of stem cells and better ways to use them for human spinal cord damage.

    DaVinci Biosciences did a cooperative study with Luis Vernaza Hospital in Ecuador showing that therapies using autologous bone marrow derived stem cells, stem cells that later form blood cells removed from the person whom they later benefit, are safe and improve the quality of life of victims who have chronic and acute spinal cord injury.

    The study was small. It included only eight people, four with chronic injury and four with acute injuries. The study used several methods to test the quality of life, pain and improvement. The treatment showed no increase in pain and yet showed improvement to the quality of life that ranged from increased sensations to better mobility and bladder control. While the degree of improvement varied in patients, all eight subjects had some improvement.

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  3. Yahoo! News

    Yahoo! News

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    If you are having trouble locating a destination on Yahoo! News, try visiting the Yahoo! News home page
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  4. Cord Blood Collection Process

    Cord Blood Collection Process

    Umbilical cord blood is human blood from the placenta and umbilical cord that is rich in stem cells. Cord blood is collected after the umbilical cord has been detached from the newborn, and sometimes used as a source of stem cells for transplantation.

    Cord blood can be stored by both public and private cord blood banks. Umbilical (more…)

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  5. YouTube – Umbilical Cord Stem Cells

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  6. Benefits Of Cord Blood Banking

    Benefits Of Cord Blood Banking

    Copyright 2006 Alvin Toh

    If you are pregnant, you probably have received information about cord blood banking. This is an opportunity for you to bank your child’s umbilical cord blood. When cord blood is banked, it is stored so that at a later time, it can be used when needed. There are several key reasons why anyone should (more…)

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  7. Cord Blood Stem Cell Breakthroughs: Cure For Diabetes?

    Cord Blood Stem Cell Breakthroughs: Cure For Diabetes?

    Cord blood, also called placental blood, is the blood that remains in the placenta and umbilical cord following birth, after the umbilical cord is cut. Generally, this blood is disposed of with the placenta and umbilical cord. There is much controversy regarding the use of stem cell research as it pertains (more…)

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  8. Latest umbilical cord blood news – UM researcher stresses hazards of unregulated stem cell clinics outside the US …

    Ok so 3 more posts today that I’ve dug up – I’m an information JUNKIE on this stuff lately. Give em a browse and let me know what ya reckon. They’re just from a few different sites I’ve been surfing lately that are generally good for information like this…

    UM researcher stresses hazards of unregulated stem cell clinics outside the US …

    Yet patients are charged large (more…)

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  9. YouTube – Gift of Life Umbilical Cord Blood Program

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  10. Latest umbilical cord blood news – Cord Blood America sponsors 2010 Brodie Golf Classic event

    If you’ve been keeping up with my blog posts lately you’ll know I’ve come to adding a few news posts from around the web on this subject. I’ve got a couple more today that are new and updated, so let me know what you think of em…

    Cord Blood America sponsors 2010 Brodie Golf Classic event

    Umbilical cord blood stem cell preservation company Cord Blood America Inc (OTCBB: (more…)

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